ExPattern

When a cell maintains a specific cellular context, for example, a phenotype, it contains a group of tightly regulated genes. This group of genes would show deterministic transcriptional activities and thus define a cellular context. When the cell moves away from this cellular context or changes to a different cellular state, the behavior of the same set of genes will not be deterministic anymore, since now, each gene is affected by various external controls. ExPattern identifies such cellular contexts: groups of statistically significant genes and samples, within which the gene expression pattern is consistent. Such contexts could potentially represent the molecular pathology of a disease. ExPattern is a context mining software that extracts contexts: groups of genes and samples within which the genes exhibit a coherent expression pattern. ExPattern can be used by biologists who need to analyze their gene expression data or drug activity data in order to extract gene regulatory mechanisms, gene-drug relations, drug-drug relations & master-slave relations from the data.
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